Shingrix Dosage And Schedule
Shingrix should be administered to immunocompetent adults aged 50 years and older and adults aged 19 years who are or will be immunodeficient or immunosuppressed because of disease or therapy as a two-dose series , 2 to 6 months apart . However, for persons who are or will be immunodeficient or immunosuppressed and who would benefit from completing the series in a shorter period, the second dose can be administered 12 months after the first. See more detailed clinical guidance.
If more than 6 months have elapsed since the first dose of Shingrix, you should administer the second dose as soon as possible. However, you do not need to restart the vaccine series.
If the second dose is given less than 4 weeks after the first dose, the second dose should be considered invalid. A valid second dose should be administered 2 months after the invalid dose .
What To Know About The Shingles Vaccine
Who needs it? The CDC recommends that everyone 50 and older get Shingrix, even if they had the earlier recommended vaccine Zostavax, or if theyve already had a bout of shingles. Older adults should also get this vaccine, whether or not they remember having had chickenpox as a child. Why? More than 99 percent of Americans over the age of 40 have been exposed to the varicella-zoster virus, even if they dont recall getting chickenpox.
How often? The CDC recommends that older adults, as described above, get this vaccine, which is given in two doses spaced two to six months apart. The shot is more than 90 percent effective after youve had both shots.
Why you need it: One in 3 people will get painful, occasionally debilitating shingles, usually after age 50, and the risk increases with age. By age 85, half of adults will have experienced at least one outbreak.
An important note: Beginning Jan. 1, 2023, Medicare enrollees with Part D wont have any out-of-pocket costs for vaccines that the CDC Advisory Committee on Immunization Practices recommends for adults, including the shingles vaccine, under the Inflation Reduction Act of 2022.
A COVID connection?
A large observational study, published in the journal Open Forum Infectious Diseases, makes clear how important it is for older adults to get both the COVID-19 vaccine and the shingles vaccine.
However, the researchers stress that people should not use these results as an excuse not to get COVID-19 shots.
Also of Interest
Who Should Not Get The Vaccine
It is safe for most people to get two doses of Shingrix. However, you should talk to your healthcare provider before getting the shingles vaccine if:
- You are pregnant
- You have severe allergies to any of the Shingrix ingredients
- You have ever experienced a severe allergic reaction to Shingrix
If you have a mild sickness, such as a cold, its usually safe to get the shingles vaccine. If you are moderately or severely ill, you should wait until you feel better to get your next dose of Shingrix.
You should still get the shingles vaccine if you dont remember having the chickenpox virus in the past and if youve had shingles previously. Shingrix can protect you against developing shingles again in the future.
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What Are The Advantages Of Getting The Shingles Vaccine
The shingles vaccine reduces your risk of getting shingles. Shingles causes a painful rash that usually develops on one side of your body or face. Some people describe the pain as an intense burning or shooting sensation. The rash is often a single strip that wraps around one side of your body or is on one side of your face. It consists of blisters that normally crust over in seven to 10 days. The rash generally clears up within a month.
For some people, the pain from the rash can last for months or even years after the rash goes away. This long-term pain is called postherpetic neuralgia , and it is the most common complication of shingles.
Great News For Us Bad News For Varicella Zoster
William Schaffner, MD, a professor in the Division of Infectious Diseases at Vanderbilt University Medical Center, told Verywell the findings are great news.
I didnt think it was pretty good dataI thought it was great data. I mean, this is a spectacular vaccine, he said.
Greg Poland, MD, the director of the Vaccine Research Group at the Mayo Clinic and the editor-in-chief of the journal Vaccine, agreed, adding the vaccine is great news for us but bad news for the virus.
Once you have chickenpox, you never get rid of it, said Poland. Its always in your body as a chronic infection.
That may not be a major concern for healthy, young people. However, Poland explained that as we get older, our immune systems start to have a harder time keeping a chronic infection in checkwhats called immunosenescence.
Given the decline in immune function with age, there have been concerns that a shingles vaccine for older people would not be successful. However, according to Poland, the fact that shingles shot can still offer protection 10 years after an older person receives it is a testament to the immunogenicity of the vaccine.
Indeed, the data show that the efficacy rate for Shingrix during the first few years after vaccination is well above 90% and is still between 80% and 90% 10 years later.
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Who Should Not Get The Shingles Vaccine
Some people shouldnt get the shingles vaccine. These people include those:
- Who currently have shingles.
- Who have had a severe allergic reaction to the shingles vaccine in the past.
- Who have tested negative for immunity to the varicella-zoster virus, meaning youve never had chickenpox. If youve never had chickenpox, you should get the chickenpox vaccine.
- Who are ill. You should wait until your illness has passed before receiving the shingles vaccine.
- Who are pregnant or breastfeeding.
Important Facts About Shingles
The virus that causes shingles is the varicella zoster virus , which is the same one that causes chickenpox. After someone recovers from chickenpox and the rash goes away, the VZV virus still remains in the body. It stays dormant, but it is possible for it to reactivate later in a persons life, which is what causes shingles.
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Can You Get The Shingrix Vaccine With Ra
The CDC currently recommends that most people with RA and other autoimmune conditions get Shingrix, especially because of their significantly higher risk of shingles. According to the American College of Rheumatology , the benefits of vaccination for people with rheumatoid arthritis usually far outweigh the relatively minor risks.
Recent research suggests that Shingrix is safe and effective in preventing shingles in people with RA. A 2021 study found that Shingrix was over 90% effective among people with RA and other autoimmune and inflammatory conditions.
Meanwhile, a 2020 study indicated that reports of flare-ups from patients with RA were rare after two doses of the shingles vaccine.
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Who Should Get Shingrix
Adults 50 years and older should get two doses of Shingrix, separated by 2 to 6 months. Adults 19 years and older who have or will have weakened immune systems because of disease or therapy should also get two doses of Shingrix. If needed, people with weakened immune systems can get the second dose 1 to 2 months after the first.
You should get Shingrix even if in the past you:
- Received varicella vaccine
There is no maximum age for getting Shingrix.
If you had shingles in the past, Shingrix can help prevent future occurrences of the disease. There is no specific length of time that you need to wait after having shingles before you can receive Shingrix, but generally you should make sure the shingles rash has gone away before getting vaccinated.
Chickenpox and shingles are related because they are caused by the same virus . After a person recovers from chickenpox, the virus stays dormant in the body. It can reactivate years later and cause shingles.
Shingrix is available in doctors offices and pharmacies.
If you have questions about Shingrix, talk with your healthcare provider.
* A shingles vaccine called zoster vaccine live is no longer available for use in the United States, as of November 18, 2020. If you had Zostavax in the past, you should still get Shingrix. Talk to your healthcare provider to determine the best time to get Shingrix.
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Can You Get Chickenpox If You’ve Been Vaccinated
Yes. About 15% 20% of people who have received one dose of varicella vaccine do still get chickenpox if they are exposed, but their disease is usually mild. Vaccinated persons who get chickenpox generally have fewer than 50 spots or bumps, which may resemble bug bites more than typical, fluid-filled chickenpox blisters. In 2006, the Advisory Committee on Immunization Practices voted to recommend routine two-dose varicella vaccination for children. In one study, children who received two doses of varicella vaccine were three times less likely to get chickenpox than individuals who have had only one dose.
Mild Side Effects Of Shingles Vaccine:
- Redness, soreness, swelling, or itching at the site of the injection .
It is safe to be around infants and young children, pregnant women, or people with weakened immune systems after you get the shingles vaccine. There is no documentation of a person getting chickenpox from someone who has received the shingles vaccine .
Some people who get the shingles vaccine will develop a chickenpox-like rash near the place where they were vaccinated. As a precaution, this rash should be covered until it disappears.
Like all vaccines, shingles vaccine is being closely monitored for unusual or severe problems by CDC and FDA.
Signs of a severe allergic reaction can include hives, swelling of the face and throat, difficulty breathing, a fast heartbeat, dizziness, and weakness. These would start a few minutes to a few hours after the vaccination. If you have a severe allergic reaction or other emergency that cant wait, call 9-1-1 or get the person to the nearest hospital. Otherwise, call your doctor.
Afterward, the reaction should be reported to the Vaccine Adverse Event Reporting System . Your doctor might file this report, or you can do it yourself through the VAERS website, or by calling 1-800-822-7967.
The shingles vaccine does not contain thimerosal .
This information was taken directly from the Shingles Vaccine Information Statement dated 10/06/2009.
For more information on possible side effects from vaccination, visit CDCs Possible Side Effects from Vaccines page.
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Plus Why It’s Important To Get The Shingles Vaccineeven If You’ve Had Shingles Before
Lambeth Hochwald is a believer that everyone has a story to tell. As a New York City-based journalist, she has been busily covering COVID-19 and its effects on everyone from college students and their parents to restaurant workers and ER doctors. Over the last few decades, she’s written for the New York Post, CNN, Parade, WebMD, Millie, Reside, the Food Network, Delish, and Architectural Digest, always with the same mandate to be compassionate, hence the hashtag #compassionatejournalism that she includes in her email auto-signature. When she’s not juggling assignments, she’s helping to teach the next generation of journalists in her role as an adjunct professor of journalism at NYU’s Arthur L. Carter Journalism Institute.
Lindsay Cook, PharmD, is a consultant pharmacist working with long-term care facilities.
Its tough enough to endure shingles once in your life. After all, its painful to experience the red blister-like bumps characteristic of shingles caused by a reactivation of the varicella-zoster virus .
Its rare to get chickenpox twice. But is it possible to get shingleswhich can feel intensely painful, like a burning, stabbing sensation, and last for two to six weeksmore than once? Here’s what you should know.
Who’s Most At Risk Of Shingles
People tend to get shingles more often as they get older, especially over the age of 70. And the older you are, the worse it can be. The shingles rash can be extremely painful, such that sufferers cannot even bear the feeling of their clothes touching the affected skin.
The pain of shingles can also linger long after the rash has disappeared, even for many years. This lingering pain is called post-herpetic neuralgia .
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How To Pay For Shingrix
Commercial insurance covers about 96% of insured people for the Shingrix vaccine. Most people with private insurance will pay under $5 for each dose.
Programs like Medicaid cover Shingrix in certain states. Medicare Parts A and B do not cover the shingles vaccine. But individuals covered under Medicare prescription drug plans, or Part D, will have their vaccines covered.
For people who do not have access to insurance, there are a number of vaccine assistance programs and affordable health coverage options available. Many of these programs provide vaccines at little or no cost.
Are Chickenpox And Shingles Serious Illnesses
The symptoms may be more severe in newborns, persons with weakened immune systems, and adults. Serious problems can occur and may include pneumonia , brain infection , and kidney problems. Many people are not aware that before a vaccine was available, approximately 10,600 persons were hospitalized, and 100 to 150 died, as a result of chickenpox in the U.S. every year.
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How Does The Shingrix Work
The shingles vaccine contains inactivated pieces of the virus, allowing the body to build immunity to the disease. In addition, it stimulates the bodys immune system to produce more antibodies without causing illness.
The presence of more antibodies helps the body confront the virus and keep the infection at bay. The vaccine also contains molecules that improve the bodys immune response to be stronger and last longer.
This process helps the body build immunity against the virus and lowers the risk of shingles-related complications such as PHN.
Im Pregnant And Have Had A Blood Test For Chickenpox What Do The Results Of This Test Show
The blood test can show that you:
- Are immune and have no sign of recent infection. You have nothing further to be concerned about.
- Are not immune and have not yet been infected. You should avoid anyone with chickenpox during your pregnancy.
- Have or recently had an infection. You should discuss what the risks are for your stage of pregnancy with your healthcare provider.
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Can You Get Shingles More Than Once
Unfortunately, it is possible to get shingles twice .
In fact, of everyone who experiences shingles, people who have weakened immune systems or are over the age of 50 years are more likely to contract the virus than others. Additionally, the longer you experience severe pain after shingles , the higher your chances of a shingles recurrence.
Interestingly, if shingles comes back, it may recur on another side of your body. Suppose the rash first appeared on the left side of your torso, for example. In that case, its likely to come back on the right side, Nidhi Ghildayal, PhD, research associate specializing in environmental health at the Harvard T.H. Chan School of Public Health in Boston, told Health.
The reason for this is that once youve had chickenpox, the virus remains alive in your nerves, explained Dr. Ghildayal. When the virus reactivates, the infected nerves become inflamed.
The skin those nerves reach also becomes inflamed, noted Dr. Ghildayal. Those rashes are most likely on the torso or chest but can also occur on your arms, head, face, eyes, or ears. A rash on one of those places might be the first sign that you should seek help from a healthcare provider.
The good news: Its uncommon to get shingles again within three years since your immune system is more prepared for the virus. But the reason shingles can recur is apparent.
After the episode, the virus becomes inactive inside your nerves but is able to reactivate in the future, explained Dr. Ghildayal.
What Does The Shingles Vaccine Do
The shingles vaccine can prevent shingles. Every year, about 1 million people in the United States get shingles. Anyone whos had chickenpox can get shingles. Thats because the varicella-zoster virus lives silently in your nervous system after you’ve had chickenpox. The virus can reactivate later in your life if your immune system is weakened. Your risk of getting shingles goes up as you get older. In the United States, 1 in 3 people will get shingles in their lifetime.
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Who Is A Candidate For The Shingles Vaccine
Adults 50 years and older. Immunocompetent adults 50 years and older should get two doses of Shingrix, 2 to 6 months apart.
Adults 19 years and older with weakened immunity. Immunity could be reduced by diseases like HIV, leukemia, or lymphoma. The immunosuppressive medicines given with organ transplants, and chemotherapy for cancer, also weaken immunity. The vaccine is safe and effective in people with multiple myeloma and other blood cancers, solid organ cancer, people with HIV, and renal transplant recipients.
People who have had shingles. Unlike chickenpox, shingles can happen again. The shingles vaccine works well if youve had shingles before. You will have stronger immunity against further attacks of shingles.
People who took Zostavax. This shingles vaccine is no longer in use in the US. People who took it should take two doses of RZV.
Do your age or health situation make you eligible for the vaccine? Weighing the benefits and potential dangers will let you make the best decision for yourself.
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