Sunday, February 25, 2024

Is The Shingles Vaccine A One Time Dose

What Are The Complications Alleged By The Plaintiffs In The Zostavax Lawsuits

Yes, you can get the shingles vaccine after getting your COVID vaccine

Thousands of Zostavax lawsuits have been filed against the drugs manufacturer Merck & Co Inc. Pharmaceuticals since 2016. The plaintiffs in these lawsuits allege that, in addition to the above complications, the administration of Zostavax causes:

  • neurological diseases or disorders, like brain inflammation and brain damage,
  • spinal cord inflammation ,
  • stiffness in the neck and back.3

Encephalitis can be very serious. In extreme cases, it can cause brain damage and death.

Further, treatment of the affliction can be difficult. Patients require extensive care with ongoing monitoring of their heart and respiratory system. Treatment also involves precise management of a persons fluid and electrolyte balances.4

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Who’s Most At Risk Of Shingles

People tend to get shingles more often as they get older, especially over the age of 70. And the older you are, the worse it can be. The shingles rash can be extremely painful, such that sufferers cannot even bear the feeling of their clothes touching the affected skin.

The pain of shingles can also linger long after the rash has disappeared, even for many years. This lingering pain is called post-herpetic neuralgia .

Vaccine Safety And Side Effects

Vaccines are very safe, and they can help keep you from getting serious or life-threatening diseases. The most common side effects for all these vaccines are mild and may include pain, swelling, or redness where the vaccine was given.

Before getting any vaccine, talk with a doctor or pharmacist about your health history, including past illnesses and treatments, as well as any allergies. A health care provider can address any concerns you have.

Its a good idea to keep your own vaccination record, listing the types and dates of your shots, along with any side effects or problems.

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Who Should Not Get The Shingles Vaccine

Some people shouldnt get the shingles vaccine. These people include those:

  • Who currently have shingles.
  • Who have had a severe allergic reaction to the shingles vaccine in the past.
  • Who have tested negative for immunity to the varicella-zoster virus, meaning youve never had chickenpox. If youve never had chickenpox, you should get the chickenpox vaccine.
  • Who are ill. You should wait until your illness has passed before receiving the shingles vaccine.
  • Who are pregnant or breastfeeding.

A Look Back At Varicella

Zoster Vaccine (zostavax) Is

Even though chickenpox and shingles are caused by the same virus, the conditions have different vaccines. The chickenpox vaccine made its debut in 1995, but a shingles vaccine didnt hit the market until about a decade later. The first shingles vaccine was Zostavax in 2006. However, this vaccine was taken off the market in 2020, following the release of another vaccine, called Shingrix, in 2017. The Centers for Disease Control and Prevention now recommends that anyone who received Zostavax be revaccinated with Shingrix.

Three groups of people absolutely should not receive the shingles vaccine. These are people who:

  • currently have shingles
  • previously had an allergic reaction to any components of the Shingrix vaccine

If you are pregnant or currently have shingles, its best to wait to get vaccinated until you are no longer pregnant or your shingles case clears up.

It may be difficult to know if you are allergic to any part of the vaccine, so speak with a doctor about any medication allergies you may have or previous reactions you experienced after vaccinations.

Most of the side effects of the shingles vaccine are limited and short-acting. Side effects usually appear in the first few days after your first or second dose of the vaccine and disappear within a few days.

Common side effects include things like:

  • arm soreness or pain where the vaccine was injected
  • swelling or redness at the injection site

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Whos Most At Risk Of Shingles

People tend to get shingles more often as they get older, especially over the age of 70. And the older you are, the worse it can be. The shingles rash can be extremely painful, such that sufferers cannot even bear the feeling of their clothes touching the affected skin.

The pain of shingles can also linger long after the rash has disappeared, even for many years. This lingering pain is called post-herpetic neuralgia .

When Should I See A Doctor Because Of The Side Effects I Experience From Shingrix

Shingrix causes a strong response in your immune system, so it may produce short-term side effects. These side effects can be uncomfortable, but they are expected and usually go away on their own in 2 or 3 days. You may choose to take over-the-counter pain medicine such as ibuprofen or acetaminophen. Contact your healthcare provider if the symptoms are not improving or if they are getting worse.

In clinical trials, Shingrix was not associated with serious adverse events. In fact, serious side effects from vaccines are extremely rare. For example, for every 1 million doses of a vaccine given, only one or two people might have a severe allergic reaction. Signs of an allergic reaction happen within minutes or hours after vaccination and include hives, swelling of the face and throat, difficulty breathing, a fast heartbeat, dizziness, or weakness. If you experience these or any other life-threatening symptoms, see a doctor right away.

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Who Should Avoid Getting The Shingrix Vaccine

You should not get Shingrix if you:

  • Have ever had a severe allergic reaction to any component of the Shingrix vaccine
  • Currently have shingles
  • Currently are pregnant or breastfeeding
  • Tested negative for immunity to varicella-zoster virus
  • Have a moderate or severe illness with a temperature of 101.3º F
  • Have gotten Varivax less than eight weeks ago

What Are The Main Differences Between Shingrix And Zostavax

What You Should Know About Shingles Vaccines | Johns Hopkins Medicine

Shingrix is a recombinant, adjuvanted zoster vaccine that was first FDA-approved in 2017. It uses the varicella-zoster glycoprotein E antigen to produce an immune response in the body. An adjuvant, or added ingredient, helps boost the bodys immune response to the virus. Because Shingrix is an inactivated vaccine, it can be used in immunocompromised patients or those with a weakened immune system.

Shingrix is administered as an injection into the muscle . It is given in two separate doses with a period of two to six months in between. The second dose is necessary to ensure long-term effectiveness.

Zostavax, approved in 2006, is a live attenuated herpes zoster vaccine. In other words, Zostavax contains a weakened version of the actual virus to produce an immune response. For this reason, it is not recommended for those who are immunocompromised. Or else, the vaccine itself could cause an infection.

Zostavax is administered as a single injection underneath the skin . It comes in a frozen version and a refrigerator-stable version. The frozen version must be kept frozen during transport and storage to ensure its effectiveness while the refrigerator-stable Zostavax can be kept in a refrigerator until it needs to be used.

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Who Should Not Get Zostavax

Some people should not get shingles vaccine :

The Shingles Prevention Study involved individuals age 60 years and older and found that Zostavax significantly reduced disease in this age group. The vaccine is currently recommended for persons 60 years of age and older.

  • A person who has ever had a life-threatening or severe allergic reaction to gelatin, the antibiotic neomycin, or any other component of shingles vaccine. Tell your doctor if you have any severe allergies.
  • A person who has a weakened immune system because of:
  • HIV/AIDS or another disease that affects the immune system,
  • treatment with drugs that affect the immune system, such as steroids,
  • cancer treatment such as radiation or chemotherapy, or
  • cancer affecting the bone marrow or lymphatic system, such as leukemia or lymphoma.
  • Women who are or might be pregnant. Women should not become pregnant until at least 4 weeks after getting shingles vaccine.
  • Someone with a minor acute illness, such as a cold, may be vaccinated. But anyone with a moderate or severe acute illness should usually wait until they recover before getting the vaccine. This includes anyone with a temperature of 101.3°F or higher.

    This information was taken from the Shingles Vaccine Information Statement dated 10/06/2009.

    I’m Pregnant And Have Recently Been Exposed To Someone With Chickenpox How Will This Exposure Affect Me Or My Pregnancy

    • Susceptible pregnant women are at risk for associated complications when they contract varicella. Varicella infection causes severe illness in pregnant women, and 10%-20% of those infected develop varicella pneumonia, with mortality reported as high as 40%.
    • Because of these risks, pregnant women without evidence of immunity to varicella who have been exposed to the virus may be given varicella-zoster immune globulin to reduce their risk of disease complications.
    • If you are pregnant and have never had chickenpox, and you get chickenpox during the:
      • First half of your pregnancy, there is a very slight risk for birth defects or miscarriage.
      • Second half of your pregnancy, the baby may have infection without having any symptoms and then get shingles later in life.
    • Newborns whose mothers develop varicella rash from 5 days before to 2 days after delivery are at risk for neonatal varicella, associated with mortality as high as 30%. These infants should receive preventive treatment with varicella-zoster immune globulin .

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    Who Is A Candidate For The Shingles Vaccine

    Healthy adults aged 50 years and older are candidates for the shingles vaccine Shingrix. There is no age limit, and you can get the Shingrix vaccine even if you have already had shingles, have had the Zostavax vaccine, or do not remember whether you have had chickenpox in the past.

    If you have already had shingles, getting the Shingrix can help protect you from the disease coming back. Studies have reported that almost every American aged 40 years and older have more than a 99% chance of having had chickenpox, and people who have had chickenpox are more likely to develop shingles in the future because both are caused by the same virusthe varicella-zoster virus.

    After having shingles, there is no duration that you need to wait before getting vaccinated, although you should wait until the rash has completely disappeared. Shringrix is given in 2 doses 2-6 months apart.

    Side effects are usually mild and may last for two to three days. No severe side effects for Shingrix have been reported so far.

    Who Should Not Get Shingrix

    Zoster Vaccine (zostavax) Is

    You should not get Shingrix if you:

    • Have ever had a severe allergic reaction to any component of the vaccine or after a dose of Shingrix.
    • Currently have shingles.
    • Currently are pregnant. Women who are pregnant should wait to get Shingrix.

    If you have a minor illness, such as a cold, you may get Shingrix. But if you have a moderate or severe illness, with or without fever, you should usually wait until you recover before getting the vaccine.

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    What Are The Benefits Of The Shingles Vaccine

    The shingles vaccines are the best way to protect you from getting shingles. The vaccines have been shown to reduce the risk of getting shingles by 50% for Zostavax® II, and to more than 90% for Shingrix®.

    For those who still get shingles after being immunized, the vaccines can reduce pain, including the type of pain that lasts after shingles.

    Make A Plan To Get 2 Doses

    • You can get Shingrix at your doctors office or pharmacy. Talk to your doctor or pharmacist about getting Shingrix.
    • Plan to get your second dose of Shingrix 2 to 6 months after your first dose.

    Five years later, I still take prescription medication for pain. My shingles rash quickly developed into open, oozing sores that in only a few days required me to be hospitalized. I could not eat, sleep, or perform even the most minor tasks. It was totally debilitating. The pain still limits my activity levels to this day.

    A 63-year-old harpist who was unable to continue playing due to shingles

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    Is Shingrix Or Zostavax Better

    Shingrix is more effective than Zostavax. Shingrix is 97% effective at preventing shingles in adults aged 50 to 69 years old whereas Zostavax is only 70% effective at preventing shingles in the same age group. Shingrix consistently prevents shingles in older adults while the effectiveness of Zostavax decreases with increasing age. However, Shingrix has more systemic side effects than Zostavax.

    What Are The Possible Side Effects Of Shingrix

    New CDC guidelines for shingles and pneumonia vaccines

    Studies show that Shingrix is safe. The vaccine helps your body create a strong defense against shingles. As a result, you are likely to have temporary side effects from getting the shots. The side effects might affect your ability to do normal daily activities for 2 to 3 days.

    Most people got a sore arm with mild or moderate pain after getting Shingrix, and some also had redness and swelling where they got the shot. Some people felt tired, had muscle pain, a headache, shivering, fever, stomach pain, or nausea. Some people who got Shingrix experienced side effects that prevented them from doing regular activities. Symptoms went away on their own in about 2 to 3 days. Side effects were more common in younger people.

    You might have a reaction to the first or second dose of Shingrix, or both doses. If you experience side effects, you may choose to take over-the-counter pain medicine such as ibuprofen or acetaminophen.

    Guillain-Barré syndrome , a serious nervous system disorder, has been reported very rarely after Shingrix. There is also a very small increased risk of GBS after having shingles.

    If you experience side effects from Shingrix, you should report them to the Vaccine Adverse Event Reporting System . Your doctor might file this report, or you can do it yourself through the VAERS websiteexternal icon, or by calling 1-800-822-7967.

    If you have any questions about side effects from Shingrix, talk with your doctor.

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    Know The Benefits And The Side Effects

    Shingrix is more than 90% effective at preventing shingles and long-term nerve pain. You may experience some short-term side effects because Shingrix causes a strong response in your immune system.

    After getting Shingrix:

    • Most people had a sore arm.
    • Many people had redness and swelling where they got the shot .
    • Many felt tired, had muscle pain, a headache, shivering, fever, stomach pain, or nausea.

    About 1 out of 6 people who got Shingrix experienced side effects that prevented them from doing regular activities like yardwork or swimming. Side effects usually go away after 2 to 3 days. Remember that the pain from shingles can last a lifetime, and these side effects should only last a few days.

    Is There A Way I Can Keep From Being Infected With Chickenpox

    Yes, make sure all your vaccines are up to date, especially if you are planning a pregnancy. Vaccination is the best way to protect yourself and those you love. If you are not immune, you should be vaccinated. You will receive two doses of varicella vaccine one month apart. You should avoid becoming pregnant for at least one month after the last vaccination. Varicella vaccine should not be given to pregnant women. If you are pregnant, have your healthcare provider give you the varicella vaccine after your baby is delivered.

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    When Should You Get Vaccinated Against Shingles

    Most people should be vaccinated against shingles at ages 50 and over. People ages 18 and over who have health conditions or take medications that can weaken the immune system should consider getting the shingles vaccine before age 50.

    For people receiving the vaccine at ages 50 and over, there is no particular time and no maximum age when you should be vaccinated.

    Vaccination against shingles can be done on its own or alongside other vaccinations, like for the flu or pneumonia. Generally, the vaccine is given in two doses, with the second dose given 2 to 6 months after the first dose.

    For people who are receiving the shingles vaccine because of an immune deficiency, the second dose can be given sooner: 1 to 2 months after the first dose.

    In this case, if possible, shingles vaccination should be timed with your immune response. This could mean waiting until after a flare-up of your condition has subsided or getting the vaccine before you receive certain immune-suppressing medications.

    7 years and remains effective afterward.

    Speak with a doctor about how often you should be vaccinated for shingles based on your specific immune system and health concerns.

    The shingles vaccine that is currently available in the United States was introduced in 2017, so you may have questions about it. Below are answers to some of the most common questions.

    How Does The Shingles Vaccine Work

    Cost of shingles vaccine at costco

    The vaccine recommended for most people is a live vaccine called Zostavax. It contains a weakened chickenpox virus . It’s similar, but not identical, to the chickenpox vaccine.

    People with a weakened immune system cannot have live vaccines. They will be offered a non-live vaccine called Shingrix. It activates the immune system but also contains an ingredient called an adjuvant, which helps to boost the response to the vaccine.

    Very occasionally, people develop chickenpox following shingles vaccination . Talk to a GP if this happens to you.

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    Shingles Vaccine Lawsuit Update

    Our law firm is handling Zostavax and Shingrix vaccine lawsuits. These vaccines were intended for the prevention of herpes zoster which is more commonly known as the shingles virus.

    These herpes lawsuits allege that the shingles vaccine was unsafe for patients. The key injury, incredibly, is that the Zostavax shingles vaccine causes shingles and zoster-related injuries. So the very thing meant to protect them against shingles actually caused shingles.

    The Zostavax shingles suits make a lot of allegations against Merck. Many of the extraneous claims have already been dismissed. Lawyers make a lot of claims when they file lawsuits like this, sometimes too many. But the core of it is plaintiffs attorneys allege that Merck knew or should have known of the risks and reactions associated with their product.

    Because Merck knew of the risks, it had a legal obligation to provide warnings. These should have fairly and accurately depicted the severity of the risks associated with the Zostavax. This is particularly true because there were better options available than Zostavax on the market.

    The Shingles Virus The New Jersey Lawsuit

    This lawsuit filed in New Jersey alleges that nearly 1,000 victims took Zostavax vaccine to avoid shingles, but instead developed a recurring strain of herpes zoster, which is more difficult to treat than usual.

    Zostavax MDL Update

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