Friday, July 12, 2024

What Is The Shingles Vaccine Called

Who Should Not Get Zostavax

What You Should Know About Shingles Vaccines | Johns Hopkins Medicine

Some people should not get shingles vaccine :

The Shingles Prevention Study involved individuals age 60 years and older and found that Zostavax significantly reduced disease in this age group. The vaccine is currently recommended for persons 60 years of age and older.

  • A person who has ever had a life-threatening or severe allergic reaction to gelatin, the antibiotic neomycin, or any other component of shingles vaccine. Tell your doctor if you have any severe allergies.
  • A person who has a weakened immune system because of:
  • HIV/AIDS or another disease that affects the immune system,
  • treatment with drugs that affect the immune system, such as steroids,
  • cancer treatment such as radiation or chemotherapy, or
  • cancer affecting the bone marrow or lymphatic system, such as leukemia or lymphoma.
  • Women who are or might be pregnant. Women should not become pregnant until at least 4 weeks after getting shingles vaccine.
  • Someone with a minor acute illness, such as a cold, may be vaccinated. But anyone with a moderate or severe acute illness should usually wait until they recover before getting the vaccine. This includes anyone with a temperature of 101.3°F or higher.

    This information was taken from the Shingles Vaccine Information Statement dated 10/06/2009.

    Why Is The Shingles Vaccine Important

    Shingles causes a painful rash and blisters and it can lead to serious complications. The most common complication is post-herpetic neuralgia , a condition that causes burning pain that can last long after the shingles rash and blisters go away. The older you are when you get shingles, the more likely you are to develop PHN.

    Getting vaccinated is the best way to prevent shingles and PHN.

    Shingles is caused by the same virus that causes chickenpox. After you have chickenpox, the chickenpox virus stays dormant in your body. The virus can activate years later and cause shingles.

    Symptoms of shingles include:

    Shingles cant spread from person to person like chickenpox. But if you have shingles, you can spread the virus to someone who isnt immune to chickenpox meaning someone who hasnt had chickenpox and isnt vaccinated against it. If that happened, the person might get chickenpox but not shingles. Learn more about shingles.

    • Adults age 50 and older
    • Adults 19 years and older who have a weakened immune system because of disease or treatments

    You need to get 2 doses of Shingrix. Youll need the second dose 2 to 6 months after the first dose. You need to get Shingrix even if you:

    • Have already had shingles
    • Have been vaccinated against shingles with Zostavax
    • Are not sure if youve had chickenpox

    Can My Grandfather With Shingles Give My Baby Daughter Chickenpox

    Yes, although people with shingles cannot pass shingles to someone else, they can pass chickenpox virus to others through direct contact with the rash. If your baby has not yet had chickenpox or the chickenpox vaccine, she could become infected with the virus and develop chickenpox.

    Unlike chickenpox that can be passed to others through coughs or sneezes, people with shingles can only pass the virus to others through direct contact with the rash. If the rash has yet to develop or has crusted, the patient cannot transmit the virus. Similarly, people who still have pain without the rash are no longer able to transmit the virus.

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    When Should You Get Vaccinated Against Shingles

    Most people should be vaccinated against shingles at ages 50 and over. People ages 18 and over who have health conditions or take medications that can weaken the immune system should consider getting the shingles vaccine before age 50.

    For people receiving the vaccine at ages 50 and over, there is no particular time and no maximum age when you should be vaccinated.

    Vaccination against shingles can be done on its own or alongside other vaccinations, like for the flu or pneumonia. Generally, the vaccine is given in two doses, with the second dose given 2 to 6 months after the first dose.

    For people who are receiving the shingles vaccine because of an immune deficiency, the second dose can be given sooner: 1 to 2 months after the first dose.

    In this case, if possible, shingles vaccination should be timed with your immune response. This could mean waiting until after a flare-up of your condition has subsided or getting the vaccine before you receive certain immune-suppressing medications.

    7 years and remains effective afterward.

    Speak with a doctor about how often you should be vaccinated for shingles based on your specific immune system and health concerns.

    The shingles vaccine that is currently available in the United States was introduced in 2017, so you may have questions about it. Below are answers to some of the most common questions.

    What Are The Advantages Of Getting The Shingles Vaccine

    The Shingles Vaccination Program has begun!

    The shingles vaccine reduces your risk of getting shingles. Shingles causes a painful rash that usually develops on one side of your body or face. Some people describe the pain as an intense burning or shooting sensation. The rash is often a single strip that wraps around one side of your body or is on one side of your face. It consists of blisters that normally crust over in seven to 10 days. The rash generally clears up within a month.

    Some people with shingles also experience additional symptoms including fever, headache, chills or upset stomach.

    For some people, the pain from the rash can last for months or even years after the rash goes away. This long-term pain is called postherpetic neuralgia , and it is the most common complication of shingles.

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    How Long Does It Take To Work

    It takes time for your body to make enough antibodies to fight off germs and protect you from certain diseases.

    Results from clinical studies of Shingrix showed that the recommended dosing schedule for Shingrix does cause an immune response.

    How long Shingrix takes to work may not be the same for everyone. The timing for you will depend on your body chemistry. In general, you should be protected from shingles soon after the second dose.

    Studies in animals showed that there was no risk with Shingrix during pregnancy. However, animal studies dont always predict the way humans would respond.

    If youre pregnant or planning to become pregnant, wait until after youve had your baby to get the Shingrix vaccine. Talk with your doctor if you have any concerns.

    There havent been enough studies to show whether Shingrix appears in breast milk.

    Until more is known, its best to wait until youve finished breastfeeding before getting Shingrix.

    What Is The Shingrix Vaccine

    Previously known as the zoster vaccine, the brand name Shingrix vaccine is the first vaccine for shingles to be approved by the FDA in more than ten years. The vaccine was developed with hopes of increasing the level of protection for aging adults against shingles and its complications. As people age, their immune systems weaken and they become more likely to experience shingles and its complications, which can put people at serious risk. The vaccine is administered into the upper arm as an injection, and people must receive two doses of the vaccine, spread out over a period of two to six months, in order to be protected.

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    What Is Mrna And What Is An Mrna Vaccine

    Messenger RNA is a bit of genetic code that teaches the bodys immune system how to make antigens, which are proteins that prompt an immune system response.

    Messenger RNA vaccines carry this code inside a fatty covering that is injected into muscle tissue. If you contract the virus later, your body will already know how to fight it.

    BioNTech co-founder Özlem Türeci told The Atlantic that mRNA vaccines were like showing our immune system a wanted poster of a foe and instructing the immune system to target that outlaw for destruction.

    Shingrix Is Not A Live Vaccine

    New Shingles Vaccine

    A live vaccine is one that contains a weakened form of a germ. Shingrix is not a live vaccine. Its an inactive vaccine, which is a vaccine thats made from a germ thats been killed.

    Because Shingrix is inactive, more people can receive it. This includes people with a weakened immune system .

    People with weakened immune systems are typically advised against receiving live vaccines. This is because on very rare occasions, live vaccines can mutate back to the full-strength germ that causes a disease.

    If this happens, people with weakened immune systems would have a much higher risk for developing the disease that the vaccine is meant to prevent.

    Shingrix is also a recombinant vaccine. This means that its made of parts of the shingles virus, such as protein, sugar, or capsid .

    There used to be an alternative shingles vaccine to Shingrix. This other vaccine was called Zostavax.

    Like Shingrix, it was approved to prevent shingles . However, Zostavax is

    Below, we briefly describe the similarities and differences between these two vaccines.

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    How Is The Shingles Vaccine Made

    The shingles vaccine available in the U.S., Shingrix®, contains a single protein from the surface of herpes zoster virus as well as two adjuvants: QS21 and monophosphoryl lipid A. QS21 is a soap-based molecule isolated from the bark of the Quillaja saponaria tree. Monophosphoryl lipid A is a detoxified form of lipopolysaccharide, a potent adjuvant taken from the surface of common bacteria.

    The first shingles vaccine, called Zostavax®, is no longer available in the U.S. However, this version contained a more concentrated version of the same live, weakened virus as the current chickenpox vaccine. It contained about 14 times the amount of weakened chickenpox virus than the vaccine for children. This amount of virus was necessary to obtain a protective response in the aging immune systems of older adults. The introduction of Shingrix vaccine was important because adjuvants in the vaccine improved immune responses in older adults and decreased the need to use large quantities of the live, weakened virus also necessary to make chickenpox vaccine. For these two reasons Zostavax is no longer available in the U.S.

    How Is Shingrix Given

    Shingrix is given as an injection into a muscle. A healthcare provider will give you this injection.

    Shingrix is usually given in a series of 2 shots:

    • the second shot may be given any time within 2 to 6 months after the first shot.

    • for people who have a weak immune system, the second shot may be given any time within 1 to 2 months after the first shot.

    You may receive this vaccine at the same time that you get a flu shot.

    Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.

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    Side Effects Of The Shingles Vaccine: Is It Safe

    Shingles is a painful rash caused by varicella zoster, the same virus responsible for chickenpox.

    If you had chickenpox as a child, the virus hasnt completely gone away. It hides dormant in your body and can reemerge many years later as shingles.

    About 1 in 3 people in the United States will develop shingles in their lifetime. This is why vaccination is important. But you should also be prepared for possible side effects. In this article, well discuss the side effects, and talk about who should get the vaccine.

    Older adults are most likely to develop shingles. This is why the shingles vaccine is recommended for people ages 50 and older.

    Shingrix is the only shingles vaccine approved by the U.S. Food and Drug Administration .

    The Shingrix vaccine is a recombinant vaccine. This means vaccine manufacturers created it by altering and purifying DNA that creates an immune response to fight the virus.

    The CDC recommends Shingrix for the prevention of shingles and related complications. The Shingrix vaccine is also recommended for anyone who has already gotten another type of shingles vaccine.

    Currently, the CDC recommends healthy people ages 50 and older get the Shingrix vaccine. Doctors administer the vaccine in two doses, which are given 2 to 6 months apart.

    The Shingrix vaccine has high success rates in protecting people against shingles.

    The Shingrix vaccine is as much as effective in preventing shingles. The same is true for Shingrix and postherpetic neuralgia.

    Medicare Drug Plans And The Shingles Vaccine

    Age and the Shingles Vaccine

    Unlike Medicare parts A and B, which are government insurance plans that cover hospital insurance and outpatient medical insurance, respectively, Medicare drug plans are private insurance policies developed by providers that have contracts with the federal government. You might purchase such a policy if you have Original Medicare or a Medigap plan and need prescription drug coverage.

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    Who Should Get The Shingrix Vaccine

    The Centers for Disease Prevention and Control recommends that healthy adults aged 50 and older receive the Shingrix vaccine in order to protect themselves against shingles. The vaccine should be administered in two doses, separated by two to six months, in order to protect against contracting the shingles virus and experiencing complications from the virus, including postherpetic neuralgia. Other shingles vaccines, such as Zostavax, do exist and have been in use since 2006. However, the Shingrix vaccine is preferred and is recommended over Zostavax. Patients who are allergic to Shingrix, need immediate vaccination and do not have access to Shingrix, or prefer the Zostavax vaccine over Shingrix may still use the Zostavax vaccine if they are healthy and aged 60 or older. However, even patients who have already received Zostavax are recommended to receive the Shingrix vaccine, as it is more effective at preventing shingles. People should get the Shingrix vaccine even if the following are true:

    • They have had shingles in the past.

    • They have received the Zostavax vaccine.

    • They are not sure if they have had chickenpox.

    Who Should Get Shingrix

    Adults 50 years and older should get two doses of Shingrix, separated by 2 to 6 months. Adults 19 years and older who have or will have weakened immune systems because of disease or therapy should also get two doses of Shingrix. If needed, people with weakened immune systems can get the second dose 1 to 2 months after the first.

    You should get Shingrix even if in the past you:

    • Received varicella vaccine

    There is no maximum age for getting Shingrix.

    If you had shingles in the past, Shingrix can help prevent future occurrences of the disease. There is no specific length of time that you need to wait after having shingles before you can receive Shingrix, but generally you should make sure the shingles rash has gone away before getting vaccinated.

    Chickenpox and shingles are related because they are caused by the same virus . After a person recovers from chickenpox, the virus stays dormant in the body. It can reactivate years later and cause shingles.

    Shingrix is available in doctors offices and pharmacies.

    If you have questions about Shingrix, talk with your healthcare provider.

    * A shingles vaccine called zoster vaccine live is no longer available for use in the United States, as of November 18, 2020. If you had Zostavax in the past, you should still get Shingrix. Talk to your healthcare provider to determine the best time to get Shingrix.

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    What Is The Brand Name Of The Shingles Vaccine

    There are 2 shingles vaccines used in the UK:

    • Zostavax, a live vaccine given as 1 dose
    • Shingrix, a non-live vaccine given as 2 doses, 2 months apart

    Most people will have the Zostavax vaccine. The Shingrix vaccine is recommended if Zostavax is not suitable for you, for example if you have a condition that affects your immune system.

    You can read more about the shingles vaccines in the patient information leaflets:

    Why Is The Shingles Vaccine Recommended

    What Are Side Effects of the Shingles Vaccine? A Doctor Explains

    The Centers for Disease Control and Prevention recommends that healthy adults 50 years and older get two doses of Shingrix two to six months apart to prevent shingles and complications from the disease. The vaccine is typically administered to adults who are 50 years and older. There is no maximum age for getting Shingrix.

    It is also given to those who have received a live zoster vaccine in the past.

    The studies report that two doses of Shingrix will be more than 90 percent effective at preventing shingles and its complication called postherpetic neuralgia.

    The vaccine protects you at least 85 percent of the time for the first four years after vaccination.

    You should get Shingrix even if you have a history as follows:

    • Already had shingles

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    How Do I Get A Covid

    The federal government is providing FDA-authorized COVID-19 vaccines free to all people living in the United States, regardless of their immigration or health insurance status. Searchvaccines.gov, text your ZIP code to 438829, or call 1-800-232-0233 to find COVID-19 vaccine locations near you.Contact yourstate health departmentto find additional vaccination locations in your area.

    If you have difficulty reaching a vaccination site, you may be able to get an in-home vaccination. Check a list of services that may offer in-home COVID-19 vaccinations in your area.

    Zostavax And The Pneumococcal Polysaccharide Vaccine

    The Summary of Product Characteristics for Zostavax, the shingles vaccine used in the UK, states that the vaccine should not be given at the same time as the Pneumococcal Polysaccharide Vaccine . This is because a clinical trial by the manufacturer had suggested this might make Zostavax less effective. However, the Department of Health advice is that the two vaccines can be given at the same time. This is based on expert advice from the Joint Committee on Vaccination and Immunisation , and on research that showed no evidence that people receiving both vaccines together had any increased risk of developing shingles. Read the abstract of the 2011 study by Tseng et al .

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