Monday, February 26, 2024

Topical Medication For Shingles Pain

What Increases The Risk Of Long

Shingles, zoster, and post-herpetic neuralgia

The risk of developing post-herpetic neuralgia increases with age. Four weeks after getting shingles,

  • 27% of 55- to 59-year-olds and
  • 73% of over 70-year-olds had nerve pain.

Women seem to be more likely to have longer-lasting nerve pain than men. Post-herpetic neuralgia is also more likely to develop if your eyes were affected by shingles.

Treatment Of Pain After Shingles

Treatment for people with PHN may include:

  • Nerve blocks: Local anesthetic or alcohol injected directly into the nerve affected
  • Thoracic epidural injections: Local injection in the space around the spinal cord
  • Antidepressant medications: Such as amitriptyline
  • Membrane stabilizers: Such as gabapentin
  • Capsaicinapplication: Topical cream applied to the affected area

Appendix 1 Medline Search Strategy

1. randomized controlled trial.pt. 2. controlled clinical trial.pt. 3. randomized.ab. 4. placebo.ab. 5. drug therapy.fs. 6. randomly.ab. 7. trial.ab. 8. groups.ab. 9. or/18 10. humans.sh. 11. 9 and 10 12. lidocaine 13. lignocaine 14. Anesthesia, Local/ or Anesthetics, Local/ 15. or/1214 16. Postherpetic 17. Postherpetic 18. Neuralgia 19. or/1618 20. 11 and 15 and 19

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Description Of The Intervention

A wide range of treatments for postherpetic neuralgia can be identified in the medical literature. Agents that are known to have been used in the treatment of postherpetic neuralgia include opioids such as: oxycodone , capsaicin cream , antidepressants , and antiepileptic drugs. A number of randomised controlled trials have shown the antiepileptic gabapentin to be very successful for treating postherpetic neuralgia . In addition, local anaesthetics such as lidocaine have been used to treat patients with postherpetic neuralgia . Novel treatments have been used, such as electrical spinal cord stimulation but generally no RCTs have been carried out on such treatments, and evidence for their effectiveness is therefore limited.

Clinicians and patients are therefore faced with an array of therapeutic options for the treatment of postherpetic neuralgia, and combined with the fact that postherpetic neuralgia is a difficult condition to treat, patients may suffer debilitating symptoms and inadequate pain relief whilst undergoing different treatment options. It is therefore important that systematic reviews of the evidence on postherpetic neuralgia treatments are undertaken. At the time of writing , the review authors are aware of the following systematic reviews that are relevant to the treatment of postherpetic neuralgia:

  • Treatments for postherpetic neuralgia .
  • Anticonvulsant drugs for acute and chronic pain .
  • Systematic lidocaine and oral analogues for neuropathic pain .

Topicals Are Not A Substitute For Medical Treatment

Amazon.com: Organic Shingles Relief Cream

Topical products can help you manage your symptoms. But they arent a substitute for proper medical treatment.

Its important to visit your doctor if youre dealing with shingles. Your doctor can prescribe antiviral drugs and other medications that can shorten the duration of your infection and help you avoid severe complications.

The following creams may be able to help you manage shingles symptoms.

Read Also: How Long Does A Shingles Outbreak Last

Best Treatments For Lasting Shingles Pain

Postherpetic Neuralgia Pain: What Works, What Doesn’t

Doctors call it postherpetic neuralgia or PHN. It’s caused by nerve damage left behind by a case of shingles. Shingles itself comes from reactivation of a chickenpox virus, varicella zoster. The virus travels down nerve fibers to cause a painful skin rash.

When the rash goes away, the pain usually goes with it. But for 12% to 15% of people the pain remains. If your shingles pain lasts eight to 12 weeks after the rash goes away, you’re part of an “unfortunate minority,” says pain researcher Andrew S.C. Rice, MD, of Imperial College, London.

“Among people with PHN, some have their pain resolve in the first year to 18 months after the shingles rash goes away,” Rice tells WebMD. “But if they have pain longer than that, it is not going to go away on its own. In either case, a person must deal with the pain.”

How Long Is Shingles Contagious

The varicella-zoster virus is contagious and can be spread from someone who has chickenpox or shingles. Although shingles is a lifelong disease, it is only contagious for some time during each episode. Shingles is contagious from the time your symptoms appear until the time that your blisters have dried or crusted, which usually happens within seven to 10 days of symptoms appearing. As long as the blistered area is covered and hands are clean the spread is contained.

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Description Of The Condition

This review is an update of a previously published review in the Cochrane Database of Systematic Reviews on ‘Topical lidocaine for the treatment of postherpetic neuralgia’ an update search has been run in both July 2008 and April 2011. Postherpetic neuralgia is a chronic pain syndrome, being the most common complication of acute herpes zoster infection. After varicella zoster infection , the virus remains dormant in dorsal root ganglia and reactivation causes shingles. Herpes zoster begins as a pain in a dermatomal distribution. Typically this is in one or two adjacent dermatomes followed by malaise and fever a few days later. A rash consisting of papules and vesicles arises in the same dermatome. The pain of postherpetic neuralgia may last for a few months or up to a lifetime. One of the most widely used definitions of postherpetic neuralgia is “pain persisting, or recurring, at the site of shingles at least one month after the onset of the acute rash” .

The number of cases of herpes zoster increases sharply with age and only about 5% of cases occur in children under 15 years . As a result, the main group of patients likely to develop postherpetic neuralgia after acute herpes zoster infection are people aged over 50 . Herpes zoster also occurs more frequently in immunosuppressed patients, and hence these people are also more likely to suffer from postherpetic neuralgia compared to their immunocompetent counterparts .

What To Do If You Think You Have Shingles

Shingles – Daily Do’s of Dermatology

If you suspect that you have shingles, its important to visit a healthcare professional as soon as possible. According to the American Academy of Dermatology , treating shingles within the first 72 hours gives you the best chance of minimizing complications like nerve pain.

Antiviral medications or other medications only available by prescription can shorten the duration of your shingles or lessen the severity.

If a cream or other topical isnt reducing your pain, its a good idea to visit your doctor again. They may recommend trying another treatment like capsaicin cream instead of lidocaine.

If a product is making your symptoms worse, its important to stop taking it right away.

You may be able to reduce your symptoms using home remedies while youre waiting to see a healthcare professional. These include applying a wet cold compress or taking a cool bath.

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How Long Does Shingles Last

The shingles virus lasts a lifetime. However, it may remain inactive for many years at a time. A shingles attack or episode may last between two and four weeks. Here is an average timeline:

  • Pain begins on a specific area of one side of the body or face.
  • A red, blotchy rash appears within five days.
  • The rash blisters. These blisters may merge and form a solid band of inflammation.
  • New blisters may form throughout a weeks time.
  • Blisters will eventually dry and scab after seven to 10 days. Minor scarring is possible.
  • Natural Remedies For Shingles

    Shingles is a viral infection that causes a painful rash. The varicella zoster virus causes this viral infection. Its the same virus that causes chickenpox.

    If you had chickenpox as a child, the shingles virus lies dormant in your body. The virus can reactivate later in life and cause a shingles rash. The rash can occur on any part of your body but typically only affects small sections.

    Pain is usually the first symptom of shingles. The rash and fluid-filled blisters form within a couple of days after the onset of pain. Some people with shingles also have a fever, sensitivity to light, and fatigue.

    According to the Centers for Disease Control and Prevention , about 1 in 3 people in the United States will develop shingles at some point in their lifetime.

    The shingles virus can last between two and six weeks. Shingles isnt life-threatening, but some people experience postherpetic neuralgia. This is when nerve fibers become damaged, causing shingles pain that lasts for weeks or months after the rash clears.

    Theres no cure for shingles, but your doctor can prescribe antiviral medication to help shorten the duration of the virus and reduce symptoms.

    Although an antiviral is an effective treatment for shingles, its not the only option. Several natural remedies may also reduce pain and discomfort.

    Dry your body completely and then wash your towel to avoid spreading the virus to others.

    • orange and yellow fruits

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    Study Assesses Relief Options Against Shingles Pain

    • Study Assesses Relief Options Against Shingles Pain

    The painkiller oxycodone is effective at treating the acute pain of shingles, an illness that often causes severe pain which can become long-lasting and sometimes even permanent.

    The study, published in the April issue of the journal Pain, is one of the first to carefully evaluate different methods to relieve pain during a course of shingles, which many patients say causes the worst pain they have ever experienced. Effective pain treatment is crucial. Not only can the pain of shingles disrupt peoples quality of life, but it is also possible that the less effectively the pain is treated, the more likely it will become a long-term problem that can change a persons life forever.

    Shingles is caused by reactivation of the varicella zoster virus, the same bug that causes chicken pox, and only people who have had chicken pox are vulnerable to shingles. About 20 to 30 percent of people will get shingles at some point in their lives the odds climb to 50 percent for people who live to the age of 85.

    For most patients, the first symptom of the infection is pain, quickly followed by a rash where the pain first appeared. The rash appears most often on one side of the chest or face, oftentimes causing dozens of small pimple-sized lesions. Some patients also get flu-like symptoms like a headache and lethargy. The illness usually lasts about three or four weeks.

    How Do Dermatologists Diagnose Shingles

    Amazon.com: Best Shingles Treatment Cream For Pain Relief. Essential ...

    A dermatologist can often diagnose shingles by looking at the rash on your skin.

    If there is any question about whether you have shingles, your dermatologist will scrape a bit of fluid from a blister. This will be sent to a lab where a doctor will look at the fluid under a high-powered microscope.

    When you have shingles, the fluid contains the virus that causes shingles. Seeing the virus confirms that you have shingles.

    Your dermatologist will also ask about your symptoms. Shingles tends to be painful.

    When the shingles rash spreads to an eye, it can affect your eyesight

    You can reduce this risk by seeing an ophthalmologist immediately.

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    Treat Your Body And Mind

    You can get worn down mentally when youâre in constant pain. Stress can make it seem even worse. Self-care starts with treating your rash, but donât stop there. Your mind and emotional state need to be cared for as well.

    5. Stick with good habits: Your bodyâs working hard to fight the varicella-zoster virus that causes shingles. To give it the right support, you can:

    • Eat nutritious food and have regular meals. Ask someone to make a run to the grocery store for fresh fruit and such if youâre not up for it.
    • Try to get a good nightâs sleep and rest anytime you need to.
    • Do gentle exercises, such as walking or stretching. Light activity can help take your mind off the pain. Keep it simple though, and check with your doctor if youâre trying something new.

    6. Distract yourself: Sometimes, the best thing you can do is to put your focus elsewhere. Here are a few things to try:

    What Triggers A Shingles Outbreak And Who Is Most At Risk

    According to Dr. Gurland, we just dont know why outbreaks happen some researchers have linked shingles with periods of excess stress, but most people who get stressed dont get shingles.

    However, shingles is more common in patients whose immune systems arent functioning normally due to cancer, medications, other infections, and other health conditions. While you dont need an immune deficiency to get shingles, said Dr. Gurland, a significant minority of patients who have it also have a suppressed immune system. The risk also increases with age , although Dr. Gurland has seen very young patients develop the disease as it doesnt discriminate.

    *Additional modalities include transcutaneous electric nerve stimulation , biofeedback and nerve blocks.

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    Treating The Pain Of Phn

    Exactly how best to deal with the pain is a difficult question. Rice led a research team that looked at 35 clinical trials of various treatments. The findings appear in the July issue of the free-access online journal PloS Medicine.

    The most important thing to realize is these are painkillers, Rice says. You are treating the pain, not the disease itself. And this is due to permanent nerve damage. It is like a stroke. We cant make the nerve damage better, but we can treat the disability. And for PHN, pain is one of those disabilities.

    What helps? Rices team found good evidence supporting:

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    Oral Pain Relief Medicines

    Capsaicin for chronic pain: arthritis, neuropathic pain and post-herpetic neuralgia

    e.g. paracetamol , aspirin ibuprofen

    e.g. paracetamol, ibuprofen diclofenac , naproxen

    e.g. ibuprofen

    e.g. diclofenac

    • paracetamol, aspirin and non-steroidal anti-inflammatories , which include ibuprofen, diclofenac and naproxen, relieve pain and reduce fever
    • paracetamol is a safe choice for most people, but it is important not to take more than recommended. Paracetamol is an ingredient in many cold and flu remedies, so be careful not to double dose
    • the maximum daily dose of paracetamol for an adult is 4 g , and no more than 1 g every 4 hours.
    • aspirin and NSAIDs are not suitable for everyone. Children under 16 years old must not take aspirin because it can cause Reyes syndrome, which is a serious condition. It should also be avoided by adolescents under 16 years old who have a viral illness
    • check with your pharmacist before taking aspirin or NSAIDs if you:
    • have a history of stomach problems, such as ulcers or indigestion
    • have asthma some asthmatics find their condition is made worse by these types of medicines
    • have kidney problems or a heart condition
    • take other medications
    • have bleeding or bruising problems
    • have an allergy to aspirin or NSAIDs
    • are pregnant or breastfeeding
    • are elderly you may be at more risk of side effects
    • are due to have any type of surgery within the next couple of days

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    Topical Pain Relief Products

    e.g. lidocaine preparations , capsaicin cream

    • topical pain relievers can be used in addition to oral pain relief medicines
    • lidocaine is a local anaesthetic and numbs the skin
    • do not apply lidocaine to broken or irritated skin avoid contact with eyes
    • capsaicin cream should NOT be used on active shingles and may only be used to help with post-herpetic neuralgia . It should be discontinued if symptoms persist for longer than 2 weeks
    • do not apply capsaicin cream to broken or irritated skin avoid contact with eyes

    Eutectic Mixture Of Local Anesthetics Cream

    EMLA cream is a prescription medication made up of a 1-to-1 ratio of 2.5 percent lidocaine and 2.5 percent prilocaine.

    A 2018 case study of one person found that EMLA cream may make an effective alternative to lidocaine cream for treating PHN in people with special situations like kidney failure. However, theres not much available research about its effectiveness. Most existing research is from the 1980s and 90s.

    A doctor can give you specific instructions on how to use EMLA cream.

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    Help Is Available For Phn

    Shingles Topical Liquid, 15 mL (0.5 fl. oz)

    Fortunately,early treatment for shingles can lower your chances of getting PHN.

    For some people, the pain becomes refractory, or resistant to treatment, explains Dr. Rosenquist. So we want to treat shingles as fast as we can ideally as soon as somebody feels a tingling or burning sensation, even before a rash develops.

    Sheadds that whenever nerve pain is involved, some people respond to treatment andsome dont.

    However,medications taken orally or injected that can target the affected nerves may beable to stun the nervous system into behaving properly. That meanstransmitting the appropriate signal to the brain.

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