Sunday, February 18, 2024

What Are The Reactions To The Shingles Shot

Allergic Reaction To Shingles Vaccination

What Are Side Effects of the Shingles Vaccine? A Doctor Explains

There is a very small chance of a severe allergic reaction to the shingles vaccine, as there is with other vaccines.

Anaphylaxis is very serious and potentially life-threatening, but it can be treated. All healthcare staff that deliver vaccinations are trained in this. With prompt treatment, people fully recover from anaphylaxis.

Shingles Disease And How To Protect Against It

Shingles, or herpes zoster, is a painful skin rash that develops on one side of the face or body. It is caused by the varicella-zoster virus , the same virus that causes chickenpox. Anyone who has had chickenpox in the past can get shingles because VZV remains in the body after a person recovers from chickenpox. VZV can reactivate many years later, causing shingles.

Shingles is more common in older adults, people who have medical conditions that weaken the immune system, and people who take medications that suppress their immune systems. Getting vaccinated is the best way to prevent shingles.

Learn more about shingles.

How Well Does Shingrix Work

Two doses of Shingrix provide strong protection against shingles and postherpetic neuralgia , the most common complication of shingles.

  • In adults 50 to 69 years old with healthy immune systems, Shingrix was 97% effective in preventing shingles in adults 70 years and older, Shingrix was 91% effective.
  • In adults 50 years and older, Shingrix was 91% effective in preventing PHN in adults 70 years and older, Shingrix was 89% effective.
  • In adults with weakened immune systems, Shingrix was between 68% and 91% effective in preventing shingles, depending on their underlying immunocompromising condition.

In people 70 years and older who had healthy immune systems, Shingrix immunity remained high throughout 7 years following vaccination.

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A Look Back At Varicella

Even though chickenpox and shingles are caused by the same virus, the conditions have different vaccines. The chickenpox vaccine made its debut in 1995, but a shingles vaccine didnt hit the market until about a decade later. The first shingles vaccine was Zostavax in 2006. However, this vaccine was taken off the market in 2020, following the release of another vaccine, called Shingrix, in 2017. The Centers for Disease Control and Prevention now recommends that anyone who received Zostavax be revaccinated with Shingrix.

Three groups of people absolutely should not receive the shingles vaccine. These are people who:

  • currently have shingles
  • previously had an allergic reaction to any components of the Shingrix vaccine

If you are pregnant or currently have shingles, its best to wait to get vaccinated until you are no longer pregnant or your shingles case clears up.

It may be difficult to know if you are allergic to any part of the vaccine, so speak with a doctor about any medication allergies you may have or previous reactions you experienced after vaccinations.

Most of the side effects of the shingles vaccine are limited and short-acting. Side effects usually appear in the first few days after your first or second dose of the vaccine and disappear within a few days.

Common side effects include things like:

  • arm soreness or pain where the vaccine was injected
  • swelling or redness at the injection site

Does The Shingles Vaccine Contain Thimerosal

Side effects of shingles vaccine : shingles

You may be concerned about additives to the shingles vaccine, like thimerosal.

Thimerosal is a preservative that contains mercury. Its added to some vaccines to prevent bacteria and other germs from growing in them. The shingles vaccine contains thimerosal.

The worry about thimerosal arose when early research linked it to autism. This connection has since been found to be untrue.

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Patient Reports Of Side Effects

During the first eight months of Shingrixs post-marketing use, the Vaccine Adverse Event Reporting System, or VAERS, received 4,381 total reports of adverse events of these 130 were serious.

For every 100,000 doses distributed, the CDC found 136 complaints filed in the system. Approximately 3.2 million doses were distributed by GlaxoSmithKline during the eight-month period of reporting analyzed by the CDC.

Fever, chills and body aches and pain, swelling and redness in the arm receiving the shot were common side effects.

Yet seven patients died within six hours to six weeks of receiving Shingrix, the CDC said. The cause of four of these deaths was cardiovascular disease . Two were immunosuppressed patients who died of sepsis. And one 86-year-old woman died after a fall. v An eighth death after the use of Shingrix was also reported to VAERS, though this was not confirmed by the CDC.

Dr. Elisabeth M. Hesse, lead author of the report and a medical officer in the CDCs Office of Immunization Safety, wrote in an email that no information in medical documentation indicated the reported deaths were related to vaccination.

She noted that the Rotashield vaccine for infants was withdrawn from the market after reports to VAERS of bowel obstruction and an investigation that verified these claims.

Do I Need To Pay For Shingles Immunisation

Vaccines covered by the NIP are free for people who are eligible. See the NIP Schedule to find out which vaccines you or your family are eligible to receive.

Eligible people get the vaccine for free, but your health care provider may charge a consultation fee for the visit. You can check this when you make your appointment.

If you are not eligible for free vaccine, you may need to pay for it. The cost depends on the type of vaccine, the formula and where you buy it from. Your immunisation provider can give you more information.

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Can You Get Shingles After Youve Been Vaccinated

While the shingles vaccine is highly effective, some people can still get shingles. However, people who do get shingles after getting the shingles vaccine usually have milder symptoms and a shorter illness. Youll also be less likely to have complications from shingles, including postherpetic neuralgia.

What Are The Possible Side Effects Of Shingrix

What You Should Know About Shingles Vaccines | Johns Hopkins Medicine

Studies show that Shingrix is safe. The vaccine helps your body create a strong defense against shingles. As a result, you are likely to have temporary side effects from getting the shots. The side effects might affect your ability to do normal daily activities for 2 to 3 days.

Most people got a sore arm with mild or moderate pain after getting Shingrix, and some also had redness and swelling where they got the shot. Some people felt tired, had muscle pain, a headache, shivering, fever, stomach pain, or nausea. Some people who got Shingrix experienced side effects that prevented them from doing regular activities. Symptoms went away on their own in about 2 to 3 days. Side effects were more common in younger people.

You might have a reaction to the first or second dose of Shingrix, or both doses. If you experience side effects, you may choose to take over-the-counter pain medicine such as ibuprofen or acetaminophen.

Guillain-Barré syndrome , a serious nervous system disorder, has been reported very rarely after Shingrix. There is also a very small increased risk of GBS after having shingles.

If you experience side effects from Shingrix, you should report them to the Vaccine Adverse Event Reporting System . Your doctor might file this report, or you can do it yourself through the VAERS websiteexternal icon, or by calling 1-800-822-7967.

If you have any questions about side effects from Shingrix, talk with your doctor.

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How Is Shingles Spread

You do not âcatchâ shingles it comes on when thereâs a reawakening of chickenpox virus thatâs already in your body. The virus can be reactivated because of a range of issues, including advancing age, medicine, illness or stress.

Anyone who has had chickenpox can get shingles. Itâs estimated that around 1 in 5 people who have had chickenpox go on to develop shingles.

Read more about the causes of shingles.

When To See A Healthcare Provider

For most people, the effects of Shingrix are mild and short-term. In very rare cases, Shingrix can cause more serious side effects.

Seek urgent medical care if you experience signs of a severe allergic reaction a few minutes or hours after your second dose of Shingrix, such as:

  • Rapid heartbeat
  • Facial swelling
  • Swelling in the throat or mouth

You should also let your healthcare provider know if your Shingrix side effects are severe or arent going away on their own.

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More Information On Side Effects

Reactions listed under possible side effects or adverse events on vaccine product information sheets may not all be directly linked to the vaccine. See Vaccine side effects and adverse reactions for more information on why this is the case.

If you are concerned about any reactions that occur after vaccination, consult your doctor. In the UK you can report suspected vaccine side effects to the Medicines and Healthcare products Regulatory Agency through the Yellow Card Scheme . See more information on the Yellow Card scheme and monitoring of vaccine safety.

Redness At Injection Site

COVID

Redness at and around the injection site is common and may appear immediately or some days after receiving Shingrix. This redness commonly develops due to a localized immune system response, which shouldnt cause further concern.

Arm redness should disappear within a few days after receiving the vaccine. However, if you experience redness with a rash or severe pain, let your doctor know as soon as possible.

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When To See A Doctor For The Possible Side Effects Of A Shingle Vaccine

Most side effects of the shingles vaccine will resolve on their own within a few days of vaccination or can be treated with over-the-counter medications like acetaminophen or ibuprofen.

In the rare case that you develop a more serious reaction after vaccination, you should call a doctor or go to a health clinic.

Medical emergency

Its rare but possible to have a serious allergic reaction to a shingles vaccine. Call emergency services or go to the nearest emergency room if you experience the following symptoms after a vaccination:

Who Should Not Receive The Shingles Vaccine

Some people should not get the shingles vaccine:

  • Individuals with weakened immune systems due to: acute and chronic leukemias lymphoma other conditions affecting the bone marrow or lymphatic system or immunosuppression due to HIV/AIDS
  • Individuals on immunosuppressive therapy
  • Individuals with a history of severe reaction after previous administration of the vaccine
  • Individuals with proven hypersensitivity to any component of the vaccine or its container, including gelatin or neomycin
  • Individuals with active untreated tuberculosis
  • Individuals who are pregnant

You should not get the vaccine if you currently have shingles. If you recently had shingles, you should wait at least one year before receiving the vaccine.

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Shingles Vaccine Side Effects

Like all vaccines, the shingles vaccines can cause side effects, but they’re generally mild and do not last long.

Common side effects that occur in at least 1 in 10 people are:

  • redness, pain, swelling, itching and warmth at the injection site

If any side effects carry on for longer than a few days, speak to your GP or practice nurse.

Tell your GP if you develop a rash after having the shingles vaccination.

A Closer Look At The Safety Data

New Shingles Vaccine

Both Shingrix and Zostavax shingles vaccines have been shown to be safe and well tolerated. Common side effects, such as soreness and redness at the injection site, are usually mild to moderate in intensity and resolve quickly on their own.

Shingrix

In 8 clinical trials of more than 10,000 participants:

  • Grade 3 reactions were common after patients received Shingrix.
  • About 1 out of 10 adults who received Shingrix reported grade 3 injection-site symptoms such as pain, redness, and swelling.
  • About 1 out of 10 reported grade 3 systemic reactions such as myalgia , fatigue , headache, shivering, fever, and gastrointestinal illness.
  • Most people who got Shingrix reported at least some pain at the injection site.

Zostavax

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How Do We Know The Vaccine Is Safe

All medicines are tested for safety and effectiveness by the Medicines and Healthcare Products Regulatory Agency . The shingles vaccine meets the high safety standards required for it to be used in the UK and other European countries. The vaccine has been given to millions of people worldwide.

Once they’re in use, the safety of vaccines continues to be monitored by the MHRA.

Fever And Feelings Of Malaise

Fever is one of the most common side effects of many vaccines, including Shingrix. This symptom often accompanies other feelings of malaise, such as muscle pains, chills, and headaches. A fever indicates that the bodys immune system is doing its job of responding to the vaccine.

Ibuprofen, acetaminophen, and other OTC fever reducers can help keep a fever and many accompanying symptoms at bay. However, if you develop a high-grade fever of 103°F or higher, reach out to your doctor immediately.

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Why Is The Shingles Vaccine Important

Shingles causes a painful rash and blisters and it can lead to serious complications. The most common complication is post-herpetic neuralgia , a condition that causes burning pain that can last long after the shingles rash and blisters go away. The older you are when you get shingles, the more likely you are to develop PHN.

Getting vaccinated is the best way to prevent shingles and PHN.

Shingles is caused by the same virus that causes chickenpox. After you have chickenpox, the chickenpox virus stays dormant in your body. The virus can activate years later and cause shingles.

Symptoms of shingles include:

Shingles cant spread from person to person like chickenpox. But if you have shingles, you can spread the virus to someone who isnt immune to chickenpox meaning someone who hasnt had chickenpox and isnt vaccinated against it. If that happened, the person might get chickenpox but not shingles. Learn more about shingles.

  • Adults age 50 and older
  • Adults 19 years and older who have a weakened immune system because of disease or treatments

You need to get 2 doses of Shingrix. Youll need the second dose 2 to 6 months after the first dose. You need to get Shingrix even if you:

  • Have already had shingles
  • Have been vaccinated against shingles with Zostavax
  • Are not sure if youve had chickenpox

Side Effects And Counseling For Reactogenicity

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In eight clinical trials of more than 10,000 immunocompetent participants 50 years or older, grade 3 reactions were common after patients received Shingrix. About 1 out of 10 adults who received Shingrix reported grade 3 injection-site symptoms such as pain, redness, and swelling. Also, about 1 out of 10 reported grade 3 systemic reactions such as myalgia, fatigue, headache, shivering, fever, and gastrointestinal illness. Most people who got Shingrix reported at least some pain at the injection site.

Local and systemic grade 3 reactions among immunocompromised adults were evaluated in six studies in five immunocompromised groups. Local grade 3 reactions occurred in 10.7% to 14.2% of RZV recipients, and systemic grade 3 reactions occurred in 9.9% to 22.3% of RZV recipients, compared with 0% to 0.3% and 6.0% to 15.5%, respectively, among placebo recipients. The most commonly reported systemic symptoms were fatigue and myalgia.

Healthcare providers should counsel patients about expected reactogenicity before administering Shingrix.

What to tell patients about the side effects of Shingrix:

Most people have a sore arm after they get Shingrix. Many people have redness and swelling on their arm spanning several inches where they got the shot. Many people also feel tired or have muscle pain, a headache, shivering, fever, stomach pain, or nausea.

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Is The Shingles Vaccine Safe

The FDA have approved the use of both shingles vaccines in healthy adults over the age of 50.

However, there are some instances in which a person should not get either vaccine â if they are pregnant or breastfeeding, allergic to any ingredient in the vaccine, or have a weakened immune system, for example.

How Long After Ive Received The Shingles Vaccine Am I Contagious

With the currently authorized shingles vaccine, Shingrix, you wont be contagious. The old vaccine, Zostavax, used a weakened form of the live varicella-zoster virus. Therefore, people worried about spreading the disease to the people around them.

Shingrix doesnt use a live version of the varicella-zoster virus. It is inactivated, which means it uses a dead version of the virus. Therefore, you have no risk of transmitting the disease to anyone.

A note from Cleveland Clinic

No one likes to get shots, especially for something youve already been vaccinated for. But the newer version of the shingles vaccine is one youll want to offer up your arm for. The Shingrix vaccine is more than 90% effective at helping you prevent shingles. Since most of us have had chickenpox in the past, the shingles vaccine is an easy way to prevent the dormant chickenpox virus from creeping up and hitting you again with shingles.

Also Check: How Many Shingles Vaccines Are There

Itchy Skin Near The Injection Site

Itchy skin, also called pruritus, can potentially occur near the injection site after receiving Shingrix. Itching, swelling, and redness arent usually a huge cause for concern, as they often occur together as a localized reaction.

Applying Benadryl gel or hydrocortisone cream around the injection area can help reduce itchy, swollen, or red skin. If the itching worsens or spreads away from the injection site, get in touch with your doctor.

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