Monday, April 15, 2024

Who Can Get The Shingles Vaccine

Can You Get Shingles After Youve Been Vaccinated

Yes, you can get the shingles vaccine after getting your COVID vaccine

While the shingles vaccine is highly effective, some people can still get shingles. However, people who do get shingles after getting the shingles vaccine usually have milder symptoms and a shorter illness. Youll also be less likely to have complications from shingles, including postherpetic neuralgia.

How Well Does Zostavax Work

Zostavax®, the shingles vaccine, reduced the risk of shingles by 51% and the risk of post-herpetic neuralgia by 67% based on a large study of more than 38,000 adults aged 60 years or older. Protection from shingles vaccine lasts about 5 years.

While the vaccine was most effective in people 60 through 69 years old, it also provides some protection for people 70 years old and older.

Adults vaccinated before age 60 years might not be protected later in life when the risk for shingles and its complications are greatest.

How Is The Shingles Vaccine Made

The shingles vaccine available in the U.S., Shingrix®, contains a single protein from the surface of herpes zoster virus as well as two adjuvants: QS21 and monophosphoryl lipid A. QS21 is a soap-based molecule isolated from the bark of the Quillaja saponaria tree. Monophosphoryl lipid A is a detoxified form of lipopolysaccharide, a potent adjuvant taken from the surface of common bacteria.

The first shingles vaccine, called Zostavax®, is no longer available in the U.S. However, this version contained a more concentrated version of the same live, weakened virus as the current chickenpox vaccine. It contained about 14 times the amount of weakened chickenpox virus than the vaccine for children. This amount of virus was necessary to obtain a protective response in the aging immune systems of older adults. The introduction of Shingrix vaccine was important because adjuvants in the vaccine improved immune responses in older adults and decreased the need to use large quantities of the live, weakened virus also necessary to make chickenpox vaccine. For these two reasons Zostavax is no longer available in the U.S.

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Make A Plan To Get 2 Doses

  • You can get Shingrix at your doctors office or pharmacy. Talk to your doctor or pharmacist about getting Shingrix.
  • Plan to get your second dose of Shingrix 2 to 6 months after your first dose.

Five years later, I still take prescription medication for pain. My shingles rash quickly developed into open, oozing sores that in only a few days required me to be hospitalized. I could not eat, sleep, or perform even the most minor tasks. It was totally debilitating. The pain still limits my activity levels to this day.

A 63-year-old harpist who was unable to continue playing due to shingles

Who Should Not Have The Shingles Vaccine

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You should not have the shingles vaccine if youve had a serious allergic reaction in the past to a previous dose of the shingles vaccine, or to any of the ingredients in the vaccine, or to a previous dose of varicella vaccine.

If you have a weakened immune system a GP or practice nurse will assess which vaccine is suitable for you. Discuss any health concerns with the GP or practice nurse before you have the vaccine.

Zostavax is not suitable for people who have a weakened immune system due to a condition, treatment or medicine.

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Can I Get The Shingles Vaccine If I Am Under Age 50

Shingrix is not recommended for adults under age 50 who have a healthy immune system.

It is recommended for adults ages 19 or over who are immunocompromised, such as people with an immune-related health condition or who are receiving immunosuppressive agents, which are medications that reduce the bodys immune response. These medications may help prevent organ rejection after an organ transplant and treat other medical conditions.

Where The Fda And Cdc Stand

According to the CDC, people ages 50 and up and immunocompromised adults ages 19 and older should get two doses of Shingrix to prevent shingles, PHN, and other possible complications. Shingrix is effective and safe for most people, including people with autoimmune disorders.

The CDC currently recommends that people with chronic medical conditions, such as RA, get the shingles vaccine. Additional CDC guidelines for people with autoimmune conditions are as follows:

  • Shingrix is usually delivered in two doses, two to six months apart. If you are immunocompromised, your healthcare provider may suggest that you get your second Shingrix dose after just one to two months instead.
  • Its usually best to wait until your symptoms are well-controlled to get Shingrix. If youre currently having a severe RA flare-up, you should typically wait until you feel better to get the shingles vaccine.
  • If youre taking immunosuppressants to manage RA symptoms, talk to your healthcare provider about the vaccine schedule that works best for you.

The Food and Drug Administration approved the use of Shingrix in 2017 for people ages 50 and older. In 2019, the FDA approved Shingrix for immunocompromised adults ages 18 and older. The FDA hasnt yet issued any specific guidelines about Shingrix and RA.

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A Look Back At Varicella

Even though chickenpox and shingles are caused by the same virus, the conditions have different vaccines. The chickenpox vaccine made its debut in 1995, but a shingles vaccine didnt hit the market until about a decade later. The first shingles vaccine was Zostavax in 2006. However, this vaccine was taken off the market in 2020, following the release of another vaccine, called Shingrix, in 2017. The Centers for Disease Control and Prevention now recommends that anyone who received Zostavax be revaccinated with Shingrix.

Three groups of people absolutely should not receive the shingles vaccine. These are people who:

  • currently have shingles
  • previously had an allergic reaction to any components of the Shingrix vaccine

If you are pregnant or currently have shingles, its best to wait to get vaccinated until you are no longer pregnant or your shingles case clears up.

It may be difficult to know if you are allergic to any part of the vaccine, so speak with a doctor about any medication allergies you may have or previous reactions you experienced after vaccinations.

Most of the side effects of the shingles vaccine are limited and short-acting. Side effects usually appear in the first few days after your first or second dose of the vaccine and disappear within a few days.

Common side effects include things like:

  • arm soreness or pain where the vaccine was injected
  • swelling or redness at the injection site

Transporting Storing And Handling Vaccines

Recommendations for new Shingles vaccine

Transport according to National vaccine storage guidelines: Strive for 5.60 Store at +2°C to +8°C. Do not freeze. Protect from light.

Zostavax must be reconstituted. Add the entire contents of the diluent container to the vial and shake until the powder completely dissolves. Reconstitute immediately after taking the vaccine out of the refrigerator. Use the reconstituted vaccine within 30 minutes.

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Are Shingles Contagious Yes Or No

If you had chickenpox when you were a child, you are at risk for shingles. Shingles occurs when the varicella-zoster virus that caused your chickenpox re-emerges after lying dormant in your nerve cells from the time of your original illness. When this occurs, you are contagious, but you can’t give someone shingles.

Who Should Get The Shingles Vaccine

The CDC recommends all healthy adults ages 50 years and older get two doses of the shingles vaccine to prevent shingles and problems that can develop after youve had the disease. The two doses should be separated by two to six months. You should get the shingles vaccine even if you:

  • Have had shingles: If youve had shingles in the past, you should get the shingles vaccine to help prevent getting the disease again. You should wait until the shingles rash is gone before getting the vaccine.
  • Arent sure if youve had chickenpox: Studies show more than 99% of Americans ages 40 and older have had chickenpox at some point in their lives. You should get the shingles vaccine whether or not you remember having chickenpox because theyre caused by the same virus.
  • Received the old shingles vaccine : Before November 18, 2020, people were vaccinated with a shingles vaccine called Zostavax. You cant get Zostavax in the United States anymore. If you were vaccinated with Zostavax, you should get vaccinated with the new shingles vaccine, Shingrix.

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Who Should Not Get Zostavax

Some people should not get shingles vaccine :

The Shingles Prevention Study involved individuals age 60 years and older and found that Zostavax significantly reduced disease in this age group. The vaccine is currently recommended for persons 60 years of age and older.

  • A person who has ever had a life-threatening or severe allergic reaction to gelatin, the antibiotic neomycin, or any other component of shingles vaccine. Tell your doctor if you have any severe allergies.
  • A person who has a weakened immune system because of:
  • HIV/AIDS or another disease that affects the immune system,
  • treatment with drugs that affect the immune system, such as steroids,
  • cancer treatment such as radiation or chemotherapy, or
  • cancer affecting the bone marrow or lymphatic system, such as leukemia or lymphoma.
  • Women who are or might be pregnant. Women should not become pregnant until at least 4 weeks after getting shingles vaccine.
  • Someone with a minor acute illness, such as a cold, may be vaccinated. But anyone with a moderate or severe acute illness should usually wait until they recover before getting the vaccine. This includes anyone with a temperature of 101.3°F or higher.

    This information was taken from the Shingles Vaccine Information Statement dated 10/06/2009.

    Routine Vaccination Of People 50 Years Old And Older

    Expert panel recommends new shingles vaccine

    CDC recommends Shingrix for the prevention of herpes zoster and related complications. CDC recommends two doses of Shingrix separated by 2 to 6 months for immunocompetent adults aged 50 years and older:

    • Whether or not they report a prior episode of herpes zoster.
    • Whether or not they report a prior dose of Zostavax, a shingles vaccine that is no longer available for use in the United States.
    • It is not necessary to screen, either verbally or by laboratory serology, for evidence of prior varicella.

    Recombinant and adjuvanted vaccines, such as Shingrix, can be administered concomitantly, at different anatomic sites, with other adult vaccines, including COVID-19 vaccines. Coadministration of RZV with adjuvanted influenza vaccine and COVID-19 vaccines is being studied.

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    Is There Anyone Who Should Not Have The Shingles Vaccination

    There are 2 shingles vaccines available in the UK:

    • Zostavax, a live vaccine given as 1 dose
    • Shingrix, a non-live vaccine given as 2 doses

    If Zostavax is not suitable for you, a GP or practice nurse will decide whether to offer you Shingrix instead.

    You should not have the shingles vaccine if you’ve had a serious allergic reaction in the past to a previous dose of the shingles vaccine, or to any of the ingredients in the vaccine, or to a previous dose of varicella vaccine.

    If you have a weakened immune system a GP or practice nurse will assess which vaccine is suitable for you. Discuss any health concerns with the GP or practice nurse before you have the vaccine.

    Zostavax is not suitable for people who have a weakened immune system due to a condition, treatment or medicine.

    Is Shingles Contagious

    The virus that causes shingles can be easily transmitted from person-to-person during the active infection phase. To avoid passing the illness to others, people with shingles should:

    • Keep the rash covered
    • Wash hands frequently and avoid touching door knobs or any other shared items
    • Avoid touching or scratching the rash
    • Avoid close contact with other people until the blisters have crusted over

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    Long Term Side Effects

    In rare cases, the live shingles vaccine, Zostavax, can cause a skin rash or shingles.

    The rash that occurs with shingles can affect any area of the body, but it often appears as a line of blisters that wraps around the torso.

    Within a few days the blisters cluster, and they continue to form for several more days. The blisters can take 2â3 weeks to heal, according to the American Academy of Dermatology.

    Other common symptoms of shingles include:

    two shingles vaccines for adults: the recombinant zoster vaccine and the zoster virus vaccine .

    Are There Side Effects

    Do I Need to Avoid Being Around Infants After Getting a Shingles Vaccine?

    Most people dont develop side effects from the shingles vaccine, but some can occur. The vaccine is injected into your arm, so pain and soreness at the injection site are common.

    The FDA also issued a warning in 2021 that there may an association between receiving the vaccine and developing Guillain-Barré Syndrome , though the relationship is poorly understood and more research is needed.

    GBS is a rare condition in which your bodys immune system attacks part of the nervous system.

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    Progesterone Hormonal Contraception And Herpes Infection In Women

    A number of studies have shown that multiple aspects of immunity in the female genital tract are controlled by sex hormones, and hormones influence susceptibility to several sexually transmitted diseases, including HSV infection.

    Evidence from animal studies has shown that treatment with female sex hormones had a significant impact on rates of HSV-2 transmission. Treatment with estradiol was found to confer some protection against vaginal HSV-2 infection in a mouse model, whereas progesterone was found to exacerbateviral infection and contributed to extensive inflammation.146-148 This may be because progesterone induces a diestrus-like state, during which mice are most susceptible to HSV-2 infection.149

    How Do We Know The Vaccine Is Safe

    All medicines are tested for safety and effectiveness by the Medicines and Healthcare Products Regulatory Agency . The shingles vaccine meets the high safety standards required for it to be used in the UK and other European countries. The vaccine has been given to millions of people worldwide.

    Once they’re in use, the safety of vaccines continues to be monitored by the MHRA.

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    What Are The Risks Of Shingles

    About one in five people who get shingles will have severe pain after the rash goes away. This pain can last months or even years. This pain is known as post-herpetic neuralgia.

    Rare complications of shingles include scarring, pneumonia, loss of hearing or vision, swelling of the brain and bacterial superinfections of the rash.

    Who Should Get The Shingrix Vaccine

    Zostavax at Rs 7900/packet

    The CDC states that anyone over 50 is a candidate for the shingles vaccine. They also recommend that you get it if you have a weakened or compromised immune system and are at least 19 years old. Certain diseases and treatments for other conditions can weaken your immune system.

    You should get it whether or not you remember having chickenpox in the past, which is caused by the same virus. Your doctor doesnt need to test for any previous infections with that virus before administering Shingrix. Its safe to assume that 99% of people born before 1980 have been exposed to the shingles virus in the form of chickenpox.

    Theres one exceptional instance where your doctor will need to decide if you need Shingrix. The vaccine is recommended only if you have a weakened immune system and are certain that youve never had chickenpox or gotten the chickenpox vaccine.

    Research is currently ongoing to determine whether or not its safe to get Shingrix at the same time as your Covid-19 vaccine. But you shouldnt get Shingrix if you have Covid-19 or have recently been exposed. This will protect your health care provider from any unnecessary exposure.

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    What Are The Advantages Of Getting The Shingles Vaccine

    The shingles vaccine reduces your risk of getting shingles. Shingles causes a painful rash that usually develops on one side of your body or face. Some people describe the pain as an intense burning or shooting sensation. The rash is often a single strip that wraps around one side of your body or is on one side of your face. It consists of blisters that normally crust over in seven to 10 days. The rash generally clears up within a month.

    Some people with shingles also experience additional symptoms including fever, headache, chills or upset stomach.

    For some people, the pain from the rash can last for months or even years after the rash goes away. This long-term pain is called postherpetic neuralgia , and it is the most common complication of shingles.

    How To Protect Yourself

    Shingles is more than an unsightly rash. After the bumps clear, you can have a long-term, painful complication called postherpetic neuralgia. “This pain can be debilitating in some people,” says Montero. “Even a light sensation, like a sheet rubbing against the skin, can cause a lot of pain.”

    Ochoa’s doctor warned her there was a good chance shingles would affect her for the rest of her life. But her rash cleared up within 6 weeks. “Fortunately, I haven’t had any side effects,” she says.

    Crystal Fiereck was also lucky that her shingles pain disappeared with her rash. She was only 12 years old, in sixth grade, when the bumps broke out on her side and back. But her luck changed at age 32, when she got shingles again, this time on the opposite side of her body. “The doctors said it’s rare , but it can happen,” she says. Again the rash faded quickly, but she still has some residual pain from her illness.

    Getting vaccinated can dramatically lower your odds of having shingles and its complications. The new vaccine, Shingrix, is more than 90% effective at preventing the disease. It’s recommended for people ages 50 and up. You’ll need two doses, given 2 to 6 months apart, to be fully protected.

    Fiereck asked her doctor about getting vaccinated and was told no. “Insurance wouldn’t cover it ⦠and it’s an expensive vaccine.”

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